Materiales
Materiales
Advancing Heterogeneous Organic Synthesis With Coordination Chemistry?Empowered Single?Atom Catalysts
18/09/2024 -
Evolution of coordination chemistry makes all the difference for single?atom catalytic organic synthesis. The relationship between the coordination structure and coordination effect of SACs and their...
Multifunctional Copper?Phenolic Nanopills Achieve Comprehensive Polyamines Depletion to Provoke Enhanced Pyroptosis and Cuproptosis for Cancer Immunotherapy
17/09/2024 -
Multifunctional Cu?Pic/HA nanopills have been designed to achieve total intracellular polyamines depletion by inhibiting intracellular polyamines synthesis, enhancing polyamines consumption and...
Electronics and Optoelectronics Based on Tellurium
16/09/2024 -
As an emerging p?type van der Waals semiconductor, tellurium (Te) exhibits great potential in advancing future electronics and optoelectronics. This review provides a comprehensive overview of the...
A Multifunctional Anisotropic Patch Manufactured by Microfluidic Manipulation for the Repair of Infarcted Myocardium
16/09/2024 -
A multifunctional anisotropic cardiac patch based on microfluidic manipulation is easily and rapidly prepared through microfluidic focusing, ion?photocrosslinking, and parallelly packing processes...
Manipulating the Electronic Properties of an Fe Single Atom Catalyst via Secondary Coordination Sphere Engineering to Provide Enhanced Oxygen Electrocatalytic Activity in Zinc?Air Batteries
16/09/2024 -
Herein, an approach to access atomically dispersed Fe sites over a defect?containing nitrogen?doped carbon matrix via secondary coordination sphere engineering is reported on. This Fe catalyst...
3D printed gelatin methacryloyl hydrogels for perfusion culture of human trabecular meshwork cells and glaucoma studies
18/09/2024 -
Graphical 3D printed human trabecular meshwork models faciliate cell behavior studies of normal and glaucomatous states and aid in drug discovery and development efforts.Glaucoma, a progressive eye...
Active diagnostic ingredients (ADIs) for PCR: A mini?bioreactor producing dNTPs with silica immobilized R5?kinases
18/09/2024 -
An immobilized enzyme bioreactor providing 2??deoxynucleoside 5??triphosphate (dNTPs) from dNMP substrates, supplying active diagnostic ingredients (ADIs) for incorporation in a PCR workflow....
Electrobiofabrication of antibody sensor interfaces within a 3D printed device yield rapid and robust electrochemical measurements of titer and glycan structure
16/09/2024 -
A 3D printed microfluidic platform is developed for rapid monitoring of monoclonal antibody (mAb) titer and quality: 8 parallel micro?channels provide robust and parallel for off?line, at?line, and...
Arctigenin Modulates Adipogenic?Osteogenic Balance in the Bone Marrow Microenvironment of Ovariectomized Rats via the MEK1/PPAR?/Wnt/??Catenin Pathway
17/09/2024 -
Arctigenin, a bioactive dibenzylbutyrolactone lignan, has demonstrated potential therapeutic effects on osteoporosis in ovariectomized (OVX) rats. Current research indicates that arctigenin (Ar)...
Allosteric Inhibition of the ?2?Adrenergic Receptor: Design and Synthesis of Cmpd?15 Analogs
17/09/2024 -
We designed and synthesized 27 new amide and dipeptide derivatives containing a substituted phenylalanine as negative allosteric modulators (NAMs) for the beta?2 adrenergic receptor (?2AR). These...
Synthesis, Molecular Docking, and Anticancer Screening of Ester?based Thiazole Derivatives
18/09/2024 -
This study investigates the potential of five compounds as novel anticancer agents. We examined their efficacy, mechanisms of action, and impact on various cancer cell lines, through a comprehensive...
New Bis(pyrazolo[5,1?b]quinazolines) and Bis(9H?xanthenediones) Linked to Alkane Cores: One?Pot Synthesis, Antibacterial Screening, and SAR Study
16/09/2024 -
Effective one?pot methods were used to synthesize some new alkane?linked bis(pyrazolo[5,1?b]quinazolines) and bis(9H?xanthenediones). The first series was produced, in 80?88% yields, via the reaction...
Neptunyl Pyrrophen Complexes: Exploring Schiff Base Chemistry with Multidentate Acyclic Ligands and Transuranics
17/09/2024 -
We present the first two neptunyl?pyrrophen compounds. Formerly synthesized with uranyl, these unique hexadentate ligands readily coordinate equatorially with neptunyl ions. The crystal structure is...
Gold?Catalyzed Synthesis of 5H?Benzo[b]indeno[2,1?d]silines by Insertion of Vinyl Carbocations into the Si–H Bond
17/09/2024 -
We have developed a gold?catalyzed cascade reaction of aryldiynes bearing a hydrosilyl group to afford a variety of unexplored 5H?benzo[b]indeno[2,1?d]silines. The reaction system is applicable to...
An Electrosynthesis of 1,3,4?Oxadiazoles from N?Acyl Hydrazones
18/09/2024 -
The 1,3,4?oxadiazole is a widely encountered motif in the areas of pharmaceuticals, materials, and agrochemicals. This work has established a mild, mediated electrochemical synthesis of...
Stereoselective Electrochemical Synthesis of E?Tetrasubstituted Haloalkenyl Chalcogenides
16/09/2024 -
Herein, we describe an electrochemical method for the synthesis of haloalkenyl chalcogenides from internal alkynes using hydrobromic and hydrochloric acids as halogenating agents, with the sole...
4?Halomethyl?Substituted Imidazolium Salts: a Versatile Platform for the Synthesis of Functionalized NHC Precursors
17/09/2024 -
N,N??Diarylimidazolium salts containing haloalkyl functional groups that are reactive with various nucleophiles are considered to be promising reagents for the preparation of functionalized...
Green synthesis of silver nanoparticles using carob leaf extract: Characterization and analysis of toxic effects in model organism Galleria mellonella L. (The greater wax moth)
18/09/2024 -
Silver nanoparticles (Ag NPs) have been used in many studies due to their inhibitory properties on microorganisms such as bacteria and viruses. In recent years, due to global problems such as...
Optimization of Brilliant Blue R photocatalytic degradation by silver nanoparticles synthesized using Chlorella vulgaris
18/09/2024 -
Synthesis of silver nanoparticles (Ag NPs) using microalgae is gaining recognition for its environmentally friendly and cost-effective nature while maintaining high activity of NPs. In the present...
Isomerism in Molecular Metal Carbonyl Clusters
18/09/2024 -
The present microreview focuses on different typologies of isomerism documented along the years for metal carbonyl clusters (MCCs), and outlines their analogies to other classes of ligand?protected...
Synthesis and Reactivity of the Amino?Functionalized ??Diketiminate Ligand Stabilized Germylene and Stannylene
18/09/2024 -
Amino?functionalized ??diketiminate stabilized chlorogermylene 1 and chlorostannylene 2 have been prepared and structurally characterized. The reactions of 1 or 2 with KOtBu afforded the...
